Concluding my focus on common deficiencies, this week turns to CLA.
CLA stands for Conjugated Linoleic Acid and is the good trans-fat that occurs naturally in dairy and meat products – especially when animals have been grass-fed, another plus for the Paleo diet. In the stomach of animals such as the goat, sheep or cows millions and millions of tiny pieces of bacteria help the animal to digest its food. They also help to covert dietary linoleic fatty acids into saturated fatty acids. While this conversion takes time and several steps, one of those steps is to create CLA, some of this never actually gets fully saturated and will show up instead in the animals milk fat and body.
28 different CLA isomers – or structural arrangements of the molecules show in CLA rich animal fat. This is very complex and different from the trans-fats created by partially hydrogenating vegetable oils. It is those lab created trans-fats that have a negative metabolic and health effect, while the CLA isomers you get from grass fed dairy and meat is more beneficial.
CLA has been touted as the “belly busting” trans fat with research in 2007 showing that in rats, supplementing their diets with CLA did not cause them to lose whole body fat, but it was found they became more insulin sensitive. When it came to supplementing CLA in mice diets it did cause rapid weight loss, but the increase in hepatic fat accumulation left the mice insulin resistant.
Many people have taken CLA as a supplement and it did seem to work for weight loss, but while the weight loss was good, at the moment we are not really sure what else it does to the body. Research into this further on different animals may help us better understand if there are any additional effects on humans. Are we more like mice or rats?
The one thing that these studies did show was that hepatic fat accumulation or loss and body fat accumulation or loss is not always in the same direction. We are seeing hepatic fat loss but no weight loss and hepatic fat gain with rapid weight loss. Those who follow low carb diets insisting that this metabolic advantage allows them to eat thousands of calories and lose weight will love the little mouse’s result! While the study on the mouse is quite well known amongst those in the carb circle with the mouse eating as much as it wants without losing or gaining weight, this metabolism does come at a price – profound liver damage.
Tests were carried out to see what effect dietary supplements of CLA would have on the body mass index, and body fat distribution. 40 volunteers participated in a 12 week double blind study some received a CLA while other received olive oil. Body fat and abdominal and hepatic fat content was assessed with an overall finding that showed CLA supplements did not show any significant change in the volunteers BMI index or in their total body fat.
Have you considered supplementing with CLA? If you have, did it have good results for you? I’d love to hear your experiences in the comments, below.